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Understanding the Difference Between Adult ADHD & Menopause Brain Fog
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Understanding the Difference Between Adult ADHD & Menopause Brain Fog

Ever feel like you’re always forgetting where you put your keys? Or, you’re constantly walking into a room, pausing, and asking yourself what you went in there for? If this sounds familiar, trust us, it’s not just you.

Brain fog is a hallmark symptom of menopause that can sometimes present similarly to attention deficit hyperactivity disorder, or ADHD. This can make things confusing. And diagnosis? Tricky. We’re here to break down the key differences and similarities between the two, and to outline some ways you can improve concentration during the menopause transition.
Is my brain fog ADHD or perimenopause—or something else?

Brain Fog

There’s no sugarcoating it: menopausal brain fog is very much a thing. In fact, a whopping 60% of women report difficulties concentrating—along with other cognition issues—during perimenopause. Fortunately, we can take comfort in knowing that these changes are usually temporary.

So what exactly causes this inconvenient symptom? Hormonal changes–you guessed it! Specifically, as estrogen levels drop during menopause, the metabolism of glucose in the brain drops (glucose being the brain’s primary fuel). This may well be why you might feel “off your game.”

Additionally, cognitive function is related to other common symptoms experienced by menopausal women: sleep disturbances, mood swings, fatigue, and hot flashes – all of which may affect our mental performance.

Menopausal brain fog is characterized by forgetfulness, difficulty concentrating, mental confusion, and feeling foggy or mentally sluggish. These symptoms may fluctuate in intensity and may be accompanied by other menopausal symptoms. And while this pesky symptom may persist for a few years, it’s ultimately short-term compared to something like overall cognitive health, which is more of a long-term consideration. ADHD symptoms, on the other hand, present a bit differently…

ADHD

When we think of ADHD, we often think of adolescents and children struggling with concentration in school, but this condition also impacts adults. In fact, diagnoses of adults with ADHD are increasing four times faster than diagnoses of children. Additionally, since girls are more likely to present with inattentive symptoms than the obvious disruptive symptoms, they’re less likely to be diagnosed in childhood.

ADHD is a neurodevelopmental disorder that typically begins in childhood and often continues into adulthood. The exact causes and risk factors for ADHD remain unclear, but studies suggest that genetics may play a role. Symptoms of ADHD typically include impulsivity, distractibility and inattention, and difficulty organizing or completing tasks.

For adult women, ADHD can present a bit differently than in males and may include:

  • Difficulties with time management
  • Trouble keeping track of belongings
  • Difficulty concentrating and finishing tasks or over-concentrating on tasks
  • Racing thoughts
  • Impulsive shopping and interrupting
  • Irritability and sensitivity

Alzheimer’s/Dementia

While many women worry that their symptoms are related to dementia or early-onset Alzheimer’s, this is not typically the case. Unlike brain fog, which can present as difficulty concentrating at work or forgetting where you parked your car, dementia tends to affect things that are more deeply ingrained like close family members’ names or the route home. It also usually worsens over time. Since dementia can be challenging to identify in the earlier stages, it’s important to know the risk factors, which include:

  • Significant family history of Alzheimer’s or dementia
  • Positive genetic testing for Alzheimer’s
  • Cardiovascular disease risks like diabetes, hypertension, obesity, smoking or high cholesterol

Anyone who notices progressively worsening symptoms that last beyond menopause or personality and behavioral changes should speak to a healthcare provider.

Does menopause make ADHD worse?

While we don’t understand a lot about brain fog and why it happens, we do know that for women with existing ADHD, the hormonal fluctuations during menopause can worsen the condition. We also know that women are very much underdiagnosed with ADHD, and for some, symptoms may not be recognized until adulthood. For many, this onset coincides with the menopause transition, due to the hormonal changes unmasking it. We hope that as healthcare further evolves to encompass women’s health, we will have a keener understanding of the exact interplay between existing ADHD and menopausal brain fog.

READ MORE: Neurodiversity and Menopause

How is ADHD treated?

There are several ways of treating and managing adult ADHD, but here are some of the most common:

Medication

The mainstay of ADHD treatment are stimulant medications, such as methylphenidate and amphetamine. They both work by targeting dopamine and norepinephrine, neurotransmitters that affect a person’s attention and concentration. There are also several non-stimulant medications approved by the FDA, including:

  • Atomoxetine and Viloxazine, which boost levels of norepinephrine
  • Guanfacine ER and Clonidine ER, which work on adrenergic receptors.

Bupropion, a medication used to treat depression that targets norepinephrine and dopamine, is sometimes used off-label.

There are dozens of different types of therapy, but Cognitive Behavioral Therapy, or CBT, is one of the most common for ADHD. CBT focuses on the interconnections between behaviors, feelings, and thoughts, and can help with identifying thought patterns and feelings that may impact behaviors. This form of therapy can also help to promote relaxation and general wellness. (Who doesn’t need a little more of that?!)

When is it time to see a doctor for ADHD?

Even though brain fog and ADHD present differently, that sliver of overlap between the two can complicate the diagnostic process. Typically, if the symptoms in question can trace back to childhood, it’s less likely to be menopause-related. However, sometimes treatment is necessary to arrive at a formal ADHD diagnosis.

If you find that your symptoms are disrupting day-to-day functioning, we recommend speaking with a healthcare professional—they may determine that psychiatry (and ADHD medication) is the best course of action and can provide a referral.

What can I do about concentration and brain fog?

Brain health is dictated by many lifestyle behaviors such as sleep, nutrition, exercise, and stress management—and no, it’s never too late to start making changes! In addition to directly benefiting brain health, lifestyle can also indirectly benefit us by impacting cardiovascular factors (e.g., hypertension, diabetes, and high cholesterol), which scientists believe are also linked to cognition.

Nutrition & Diet

Diet plays a clear and integral role in every aspect of brain function. And although there’s no one best diet for everyone, the Mediterranean diet has been associated (correlation, not causation) with better cognition, as well as better sleep and cardiovascular health.

READ MORE: 9 Foods (& Drinks) That Help With Menopausal Brain Fog

Hydration

The brain is composed of 80% water, and it’s necessary for energy production. Even small amounts of dehydration can cause symptoms such as brain fog, fatigue, dizziness, confusion, and brain shrinkage (you read that right…your brain can actually shrink!). So stay hydrated! A good rule of thumb: drink enough so your urine is clear or pale yellow.

Single-tasking

Although we may be conditioned to multi-task, as humans, we’re not hardwired to excel at this. Contrary to popular belief, it’s actually been shown to take longer, as well as result in more errors. Research also indicates that “media multitasking” (watching TV while scrolling through your emails, for example) affects memory. Instead, prioritize doing one thing at a time. Just taking a moment to really observe process where you’re parking your car—rather than responding to texts as you walk away—can make a difference.

Supplements

While we believe that nutrition should be the primary source of brain-healthy ingredients, we recognize that supplements are sometimes necessary. The most evidence-based supplement recommendation for brain health is to correct documented deficiencies in B12, folate, and Vitamin D.

Outside of correcting these common deficiencies, women in menopause might also consider Omega-3 supplementation and a daily multivitamin.

READ MORE: Elektra Guide to Supplements For Menopause

What about hormone replacement therapy?

Hormone therapy for brain fog

Unfortunately, current data does not show that the use of menopause hormone therapy/MHT (previously referred to as hormone replacement therapy/HRT) clears brain fog. Results are mixed, and the reassuring thing is that while hormone therapy may not directly help with brain fog, it will not worsen it either.

A related (and exciting!) area of research is currently examining hormone therapy as a way to stave off future cognitive changes. At present, it is still unclear whether hormone therapy use around the time of menopause will prevent dementia. Because of that, hormone therapy is not recommended at this point solely for preservation of cognitive function and Alzheimer’s prevention. For ADHD, on the other hand, hormone therapy can play a role…

Hormone therapy for…ADHD?

Sometimes, women with ADHD who are already taking stimulant medication but find that their symptoms are worsening during menopause notice improvements when starting hormone therapy. This is because hormone therapy can amplify the effects of stimulants.

What about antihistamines?

You may have seen some buzz around an online trend involving the use of antihistamines and acid blockers to manage menopause symptoms—including brain fog. The theory seems to be based on a treatment for mast cell activation syndrome (MCAS), a condition that causes frequent anaphylactic reactions, such as symptoms like swelling and hives.

Because there is a connection between estrogen and progesterone and histamine (the chemical that triggers MCAS flare-ups and allergy attacks), the idea is that preventing a histamine response could stop menopause symptoms in the same way it does for MCAS.

This is, however, just a theory, and while we may have anecdotal reports promoting it, we don’t currently have any scientific evidence that it works. That said, these are relatively safe, over-the-counter medications. So, while we wouldn’t recommend it based on current evidence, it’s unlikely to be harmful. The most important thing is that you discuss your symptoms with your provider to ensure you don’t miss another diagnosis that could be responsible for your symptoms.

The bottom line

Changes in hormone levels, and decreasing estrogen levels in particular, are responsible for a whole lot of menopause symptoms, including brain fog. And even though this symptom is generally temporary, brain fog can be frustrating and impact general well-being. Plus, the overlap between symptoms and impairments of ADHD can cause confusion around when to worry. If in doubt, it’s always worth speaking to a provider about.

Interested in care? Learn more and book a visit with an Elektra clinician.

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